Prenatal PCB-153 Exposure and Decreased Birth Weight: Verner et al. Respond
نویسندگان
چکیده
Verner et al. (2013) recently questioned whether the association between cord levels of PCB-153 (poly chlorinated biphenyl-153) and birth weight reported in our recent metaanalysis (Govarts et al. 2012) might be attributable to the influence of gestational weight gain (GWG), a factor that may be related to both PCB-153 concentrations and birth weight. By using simulated data in a physiologically based pharmaco kinetic (PBPK) model, Verner et al. (2013) concluded that
منابع مشابه
Prenatal PCB-153 Exposure and Decreased Birth Weight: The Role of Gestational Weight Gain
Verner et al. (2013) recently questioned whether the association between cord levels of PCB-153 (poly chlorinated biphenyl-153) and birth weight reported in our recent metaanalysis (Govarts et al. 2012) might be attributable to the influence of gestational weight gain (GWG), a factor that may be related to both PCB-153 concentrations and birth weight. By using simulated data in a physiologicall...
متن کاملIs the Relationship between Prenatal Exposure to PCB-153 and Decreased Birth Weight Attributable to Pharmacokinetics?
BACKGROUND A recent meta-analysis based on data from > 7,000 pregnancies reported an association between prenatal polychlorinated biphenyl (PCB)-153 exposure and reduced birth weight. Gestational weight gain, which is associated negatively with PCB levels in maternal and cord blood, and positively with birth weight, could substantially confound this association. OBJECTIVE We sought to estimat...
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عنوان ژورنال:
دوره 122 شماره
صفحات -
تاریخ انتشار 2014